Hormones
Estradiol
LOINC 14715-7 · pg/mL
What it is
Estradiol is the main form of estrogen, a key sex hormone. Levels vary with the menstrual cycle, pregnancy, menopause and across sexes.
Why it matters
It is central to reproductive health, bone health and the menstrual cycle, and is checked in fertility and menopause assessments.
What high values can mean
A higher value can be normal at certain cycle phases or relate to specific conditions or treatments.
What low values can mean
A lower value can occur around menopause or with reduced ovarian or testicular function.
How to improve it
Estradiol reflects reproductive physiology; results are interpreted in the context of your cycle, age and sex.
Food & lifestyle
Lifestyle has limited direct effect; a healthy weight and not smoking support hormonal balance generally.
Preparing for the test
Timing matters in menstruating women — the cycle day affects results, so note it for your clinician.
When to talk to a doctor
Discuss abnormal estradiol with a doctor, interpreted with FSH and your clinical context.
Related markers
Sources
- MedlinePlus (NIH)
- Testing.com (AACC)
Content reviewed on June 26, 2026
Medical disclaimer
This content is for educational purposes only. It is not medical advice and does not diagnose, treat, or prevent any condition. Reference ranges vary between laboratories — always use the range printed on your report and discuss your results with a healthcare professional.
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