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Hormones

DHEA-S

LOINC 2191-5 · mcg/dL

What it is

DHEA-S is a hormone made by the adrenal glands. It is a building block the body can turn into other sex hormones.

Why it matters

It helps assess adrenal function and is checked when there are signs of hormone imbalance.

What high values can mean

A higher value can relate to conditions that overproduce adrenal hormones and may cause acne or excess hair growth.

What low values can mean

A lower value naturally declines with age and can relate to reduced adrenal activity.

How to improve it

DHEA-S reflects adrenal hormone production; it is not changed by everyday lifestyle, and supplements should only be used under guidance.

Food & lifestyle

No specific food changes DHEA-S; do not take DHEA supplements without medical advice.

Preparing for the test

A blood test; fasting is not required — follow your lab's instructions.

When to talk to a doctor

Discuss an abnormal DHEA-S with a doctor, especially with signs of hormone imbalance.

Related markers

Sources

  • MedlinePlus (NIH)
  • Testing.com (AACC)

Content reviewed on June 26, 2026

Medical disclaimer

This content is for educational purposes only. It is not medical advice and does not diagnose, treat, or prevent any condition. Reference ranges vary between laboratories — always use the range printed on your report and discuss your results with a healthcare professional.

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