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Hormones

PSA Free

LOINC 10886-0 · ng/mL

What it is

Free PSA is the portion of prostate-specific antigen circulating unbound to proteins. It is used together with total PSA.

Why it matters

Comparing free to total PSA helps refine prostate-cancer risk and biopsy decisions.

What high values can mean

Interpretation depends on the free-to-total ratio rather than the free value alone.

What low values can mean

Interpretation depends on the free-to-total ratio rather than the free value alone.

How to improve it

Free PSA is a diagnostic measure, not something changed by lifestyle.

Food & lifestyle

No food changes free PSA; it is part of prostate testing.

Preparing for the test

Drawn with total PSA; avoid ejaculation and vigorous cycling for a couple of days before — follow your lab.

When to talk to a doctor

Free PSA is interpreted by a doctor as part of the total/free PSA picture.

Related markers

Sources

  • MedlinePlus (NIH)
  • Testing.com (AACC)

Content reviewed on June 26, 2026

Medical disclaimer

This content is for educational purposes only. It is not medical advice and does not diagnose, treat, or prevent any condition. Reference ranges vary between laboratories — always use the range printed on your report and discuss your results with a healthcare professional.

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