Hormones
Leptin
LOINC 21365-2 · ng/mL
What it is
Leptin is a hormone released by fat cells that signals the brain about your energy stores and helps regulate appetite.
Why it matters
It offers insight into appetite regulation and metabolic health, particularly in the context of weight.
What high values can mean
A higher value usually tracks with more body fat; the body can become less responsive to leptin's "full" signal.
What low values can mean
A lower value tracks with less body fat and can increase appetite.
How to improve it
Gradual weight management, good sleep, regular activity and limiting ultra-processed foods support healthier leptin signalling.
Food & lifestyle
Whole foods, fibre, protein and good sleep support appetite regulation; ultra-processed foods and poor sleep work against it.
Preparing for the test
A blood test, sometimes fasting — follow your lab's instructions.
When to talk to a doctor
Discuss leptin results with a clinician as part of a broader metabolic and weight assessment.
Related markers
Sources
- Testing.com (AACC)
- NIH (NCBI)
Content reviewed on June 26, 2026
Medical disclaimer
This content is for educational purposes only. It is not medical advice and does not diagnose, treat, or prevent any condition. Reference ranges vary between laboratories — always use the range printed on your report and discuss your results with a healthcare professional.
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