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Coagulation

Fibrinogen

LOINC 3255-7 · mg/dL

Ranges

Reference range: 200–400 mg/dL

What it is

Fibrinogen is a protein made by the liver that is essential for blood to clot. It is also an inflammation-responsive protein.

Why it matters

It helps assess clotting ability and bleeding risk, and can reflect inflammation.

What high values can mean

A higher value can reflect inflammation and is associated with a greater tendency to clot.

What low values can mean

A lower value can impair clotting and raise bleeding risk, from liver issues or being used up in clotting.

How to improve it

Fibrinogen follows liver health and inflammation; care targets the underlying cause.

Food & lifestyle

Not smoking and an anti-inflammatory lifestyle support healthier fibrinogen; the cause matters more than diet alone.

Preparing for the test

A blood test; fasting is not required — follow your lab's instructions.

When to talk to a doctor

An abnormal fibrinogen is interpreted by a doctor with your clotting tests and clinical picture.

Related markers

Sources

  • MedlinePlus (NIH)
  • Testing.com (AACC)

Content reviewed on June 26, 2026

Medical disclaimer

This content is for educational purposes only. It is not medical advice and does not diagnose, treat, or prevent any condition. Reference ranges vary between laboratories — always use the range printed on your report and discuss your results with a healthcare professional.

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